The Buffalo Bills will inaugurate their new stadium, Highmark Stadium, during Week 2, hosting the Detroit Lions on Thursday Night Football on September 17, with the game broadcasted by Prime Video. This new $2 billion facility replaces their previous home, Rich Stadium, which opened in 1973. The Bills have a strong track record, winning their last four home openers since 2022 and averaging 38.5 points per game. The NFL is set to release the full schedule on Thursday.
