The Eagles (10-5) face the Bills (11-4) in Week 17, spotlighting key matchups like the Eagles’ run defense against James Cook, who leads the NFL in rushing yards. Josh Allen poses a significant challenge to Philly’s defense, while the Eagles’ defensive line aims to pressure the Bills’ offensive line. Additionally, Jalen Hurts must contend with Buffalo’s strong pass defense, and Fred Johnson will protect against Greg Rousseau in the absence of Lane Johnson.
