As the 49ers kick off the 2025 NFL season against the Seahawks, five key players to watch include CB Deommodore Lenoir, RB Christian McCaffrey, DE Nick Bosa, QB Brock Purdy, and DE Mykel Williams. With a mix of rookies and veterans, the 49ers aim for a strong start following a challenging previous season, facing a formidable Seahawks team.
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Five 49ers to watch in Week 1 showdown vs. Seahawks as 2025 NFL season kicks off
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