The Los Angeles Rams suffered a disappointing loss to the San Francisco 49ers in their 2026 NFL season opener in Melbourne, with a final score of 27-7. Quarterback Brock Purdy threw three touchdown passes, while Rams QB Matthew Stafford struggled with accuracy and a significant interception. Notably, star acquisition Myles Garrett failed to record any stats, and the Rams’ rushing defense was overpowered. Despite the loss, the 49ers showed promise, but rookie receiver De’Zhaun Stribling was carted off with a concerning leg injury.
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Rams Lose to 49ers, Fall to Last Place in NFC West
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