The 49ers have ruled out kicker Eddy Pineiro (right hamstring) and linebacker Tatum Bethune (ankle) for their upcoming game, with Pineiro expected to miss multiple weeks and Bethune also out due to a high-ankle sprain. Defensive end Robert Beal is doubtful due to a concussion, while linebacker Luke Gifford is questionable; however, quarterback Brock Purdy and wide receiver Ricky Pearsall have no injury designations after full participation in practice.
