49ers wide receiver Brandon Aiyuk is likely to start the season on reserve/physically unable to perform due to ongoing recovery from knee surgery, potentially sidelining him for at least the first four games. While there’s a slight chance he could play in the season opener, the organization prefers to take a cautious approach, starting him on PUP when training camp begins on July 22.
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Report: Brandon Aiyuk likely starts season on PUP, but 49ers haven't ruled him out for Week 1
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