Pittsburgh Pirates pitcher Paul Skenes remains winless against the St. Louis Cardinals, falling to 0-4 after a 2-1 loss, marking the most starts without a win against St. Louis since JT Brubaker. Despite a solid performance allowing two runs on three hits over six innings, Skenes was hurt by a critical two-out, two-run double from Alec Burleson in the sixth. With only three runs of support in his five career starts against the Cardinals, Skenes and the Pirates continue to struggle offensively, losing six straight and nine of their last ten games.